DNA Ploidy*

Additional Info

  • Methodology: Flow Cytometry
  • Test Description:

    DNA stain propidium iodide is used to determine S-phase cell cycle fraction and DNA index as indicators of DNA ploidy.

  • Clinical Significance:

    DNA analysis is, after immunofluorescence, the second most important application of flow cytometry. By measuring the DNA content of individual cell, we can obtain information about their ploidy, of particular relevance in tumors, and, for a population, the distribution of cells across the cell cycle.

  • Specimen Requirements:

    Flow cytometry testing can be performed on bone marrow aspirate, peripheral blood, fresh bone marrow core biopsy, unfixed tissue, and body fluids. Please see full specimen requirements for either Standard Leukemia/Lymphoma Analysis or Extended Leukemia/Lymphoma Analysis.

  • Storage & Transportation:

    Specimens should be received within 24-48 hours from collection to ensure acceptable cell viability. Peripheral blood and bone marrow aspirate specimens can be stored and transported at room temperature. Other tissue biopsies and body fluids should be refrigerated but not frozen; please use a cold pack to transport these specimens, making sure the cold pack is not in direct contact with the specimen.

  • Level of Service: Global
  • Turnaround Time: 1 day
  • ***: The CPT codes provided with our test descriptions are based on AMA guidelines and are for informational purposes only. Correct CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.